Recombinant Human GAS7, GST-tagged

• Cat.No.: GAS7-13163H
• Product Overview: Recombinant Human GAS7 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 184-382a.a.
• Description: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinsons disease, Alzheimers disease, cataract formation, and atherosclerosis.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GAS7 growth arrest-specific 7 [ Homo sapiens ]
• Official Symbol: GAS7
• Synonyms: GAS7; growth arrest-specific 7; growth arrest-specific protein 7; KIAA0394; MGC1348; MLL/GAS7 fusion protein; MLL/GAS7
• Gene ID: 8522
• mRNA Refseq: NM_001130831
• Protein Refseq: NP_001124303
• MIM: 603127
• UniProt ID: O60861
• Chromosome Location: 17p13.1
• Function: actin filament binding; sequence-specific DNA binding transcription factor activity