Recombinant Human GAS6 protein, His-tagged

• Cat.No.: GAS6-383H
• Product Overview: Recombinant Human Growth Arrest-specific Protein 6 is produced by our Mammalian expression system and the target gene encoding Ala31-Ala678 is expressed with a 6His tag at the C-terminus.

Specification

• Description: GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
• Source: HEK293
• Species: Human
• Tag: His
• Predicted N Terminal: Ala
• Form: Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
• Molecular Mass: The recombinant human GAS6 consists of 641 amino acids and predicts a molecular mass of 71.2 kDa.
• Protein length: Ala31-Ala678
• Endotoxin: Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Store at < -20ºC, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μl. Centrifuge the vial at 4℃ before opening to recover the entire contents.
• Shipping: The product is shipped on dry ice/polar packs.
  Upon receipt, store it immediately at the temperature listed below.

Gene Information

• Gene Name: GAS6
• Official Symbol: GAS6
• Synonyms: AXLLG; AXLLGAXL stimulatory factor; AXSFAXL receptor tyrosine kinase ligand; Gas6; GAS-6; growth arrest-specific 6; growth arrest-specific protein 6
• Gene ID: 2621
• mRNA Refseq: NM_000820.4
• Protein Refseq: NP_000811.1
• MIM: 600441
• UniProt ID: Q14393