Recombinant Human Gamma-Glutamyl Hydrolase (conjugase, folylpolygammaglutamyl hydrolase), His-tagged
| Cat.No. : | GGH-1399H |
| Product Overview : | Recombinanthuman GGHprotein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventionalchromatography techniques. |
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| Cat. No. : | GGH-1399H | ||
| Description : | GGH is a homodimericprotein that catalyzes the cleavage of the gamma-glutamyl chain offolylpoly-gamma-glutamyl substrates and is a central enzyme in folyl andantifolyl poly-gamma-glutamate metabolism. GGH may play an important role inthe bioavailability of dietary pteroylpolyglutamates and in the metabolism ofpteroylpolyglutamates and antifolates. | ||
| Form : | Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl. | ||
| Molecular Weight : | 35.9 kDa(315aa), confirmed by MALDI-TOF. | ||
| Purity : | > 95%by SDS-PAGE | ||
| Concentration : | 0.5mg/ml(determined by Bradford assay) | ||
| Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MRPHGDTAKK PIIGILMQKC RNKVMKNYGR YYIAASYVKY LESAGARVVPVRLDLTEKDY EILFKSINGI LFPGGSVDLR RSDYAKVAKI FYNLSIQSFDDGDYFPVWGT CLGFEELSLL ISGECLLTAT DTVDVAMPLN FTGGQLHSRM FQNFPTELLL SLAVEPLTANFHKWSLSVKN FTMNEKLKKF FNVLTTNTDG KIEFISTMEG YKYPVYGVQW HPEKAPYEWK NLDGISHAPNAVKTAFYLAEFFVNEARKNNHHFKSESEEE KALIYQFSPI YTGNISSFQQ CYIFD | ||
| Storage : | Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles. | ||
| OfficialSymbol : | GGH | ||
| nullValue_other : |
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| Gene Name | GGH gamma-glutamyl hydrolase(conjugase, folylpolygammaglutamyl hydrolase) [ Homo sapiens ] |
| Synonyms | GGH; gamma-glutamyl hydrolase (conjugase,folylpolygammaglutamyl hydrolase); GH; gamma-glutamyl hydrolase; gamma-Glu-Xcarboxypeptidase; OTTHUMP00000226541; EC 3.4.19.9; Gamma-glutamyl hydrolase; Conjugase; Gamma-Glu-Xcarboxypeptidase; OTTHUMP00000226541; OTTHUMP00000226558 |
| Gene ID | 8836 |
| mRNA Refseq | NM_003878 |
| Protein Refseq | NP_003869 |
| MIM | 601509 |
| UniProt ID | Q92820 |
| Chromosome Location | 8q12.3 |
Not For Human Consumption!
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