Recombinant Human GABBR2, GST-tagged
Cat.No. : | GABBR2-13088H |
Product Overview : | Recombinant Human GABBR2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Availability | April 04, 2025 |
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Species : | Human |
Source : | E.coli |
Tag : | GST |
Protein Length : | 59-386a.a. |
Description : | The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name | GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 [ Homo sapiens ] |
Official Symbol | GABBR2 |
Synonyms | GABBR2; gamma-aminobutyric acid (GABA) B receptor, 2; G protein coupled receptor 51 , GPR51; gamma-aminobutyric acid type B receptor subunit 2; GABABR2; GPRC3B; HG20; gb2; GABA-BR2; GABA-B-R2; GABA-B receptor 2; GABA-B receptor, R2 subunit; G protein-coupled receptor 51; G-protein coupled receptor 51; gamma-aminobutyric acid B receptor 2; GPR51; HRIHFB2099; FLJ36928; |
Gene ID | 9568 |
mRNA Refseq | NM_005458 |
Protein Refseq | NP_005449 |
MIM | 607340 |
UniProt ID | O75899 |
Chromosome Location | 9q22.1-q22.3 |
Pathway | Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Class C/3 (Metabotropic glutamate/pheromone receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; G protein gated Potassium channels, organism-specific biosystem; GABA B receptor activation, organism-specific biosystem; GABA receptor activation, organism-specific biosystem; |
Function | G-protein coupled GABA receptor activity; receptor activity; signal transducer activity; |
◆ Recombinant Proteins | ||
GABBR2-4630H | Recombinant Human GABBR2 Protein, GST-tagged | +Inquiry |
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GABBR2-4629H | Recombinant Human GABBR2 Protein | +Inquiry |
GABBR2-13088H | Recombinant Human GABBR2, GST-tagged | +Inquiry |
GABBR2-5178HF | Recombinant Full Length Human GABBR2 Protein, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
GABBR2-6072HCL | Recombinant Human GABBR2 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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