Recombinant Human FXYD3, His-tagged

• Cat.No.: FXYD3-13056H
• Product Overview: Recombinant Human FXYD3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-87a.a.
• Description: This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FXYD3 FXYD domain containing ion transport regulator 3 [ Homo sapiens ]
• Official Symbol: FXYD3
• Synonyms: FXYD3; FXYD domain containing ion transport regulator 3; FXYD domain containing ion transport regulator 3 , PLML; FXYD domain-containing ion transport regulator 3; MAT 8; phospholemman-like protein; mammary tumor 8 kDa protein; chloride conductance inducer protein Mat-8; MAT8; PLML; MGC111076
• Gene ID: 5349
• mRNA Refseq: NM_001136007
• Protein Refseq: NP_001129479
• MIM: 604996
• UniProt ID: Q14802
• Chromosome Location: 19q13.11-q13.12
• Function: ATPase binding; chloride channel activity; ion channel activity