Recombinant Human FRS3, GST-tagged

• Cat.No.: FRS3-13009H
• Product Overview: Recombinant Human FRS3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: N-term-303a.a.
• Description: The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FRS3 fibroblast growth factor receptor substrate 3 [ Homo sapiens ]
• Official Symbol: FRS3
• Synonyms: FRS3; fibroblast growth factor receptor substrate 3; FRS2B; FRS2beta; SNT 2; FRS2-beta; FGFR substrate 3; FGFR-signaling adaptor SNT2; suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor); SNT2; SNT-2; MGC17167
• Gene ID: 10817
• mRNA Refseq: NM_006653
• Protein Refseq: NP_006644
• MIM: 607744
• UniProt ID: O43559
• Chromosome Location: 6p21.1
• Pathway: Downstream signaling of activated FGFR, organism-specific biosystem; FRS2-mediated cascade, organism-specific biosystem; Neurotrophic factor-mediated Trk receptor signaling, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by FGFR, organism-specific biosystem
• Function: fibroblast growth factor receptor binding; insulin receptor binding