Recombinant Human FNTA Protein (M1-Q379), His/Strep tagged

• Cat.No.: FNTA-0471H
• Product Overview: Recombinant Human 6His-strepII-TEV-GG-FNTA(M1-Q379 end) Protein was expressed in E. coli.

Specification

• Description: Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
• Source: E. coli
• Species: Human
• Tag: His&Strep
• Form: Liquid
• Protein length: M1-Q379
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: FNTA farnesyltransferase, CAAX box, alpha [ Homo sapiens (human) ]
• Official Symbol: FNTA
• Synonyms: FNTA; farnesyltransferase, CAAX box, alpha; protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; FPTA; PGGT1A; protein prenyltransferase alpha subunit repeat containing 2; PTAR2; FTase-alpha; GGTase-I-alpha; farnesyl-protein transferase alpha-subunit; ras proteins prenyltransferase subunit alpha; type I protein geranyl-geranyltransferase alpha subunit; MGC99680
• Gene ID: 2339
• mRNA Refseq: NM_002027
• Protein Refseq: NP_002018
• MIM: 134635
• UniProt ID: P49354