Recombinant Human Fibroblast Growth Factor 7

• Cat.No.: FGF7-5416H
• Product Overview: Recombinant human FGF7is Expressed in HEK 293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Non
• Description: FGF7 is expressedin human 293 cells as a monomeric glycoprotein with an apparent MW 17 and 30kDa. This cytokine is produced in a human cell expression system withserum-free, chemically defined media. Authentic glycosylation contributes tostability in cell growth media and other applications. The cytokine isgreater than 95% pure.
• MolecularWeight: 17 and 30 kDamonomer, glycosylated
• Purity: > 95% The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel wasstained with Coomassie blue.
• Endotoxin Level: Endotoxin Free<1 EU/ug
• Biological Activity: 10 to 40 ng/mL ED50
• Specific Activity: The specificactivity was determined by the dose-dependent stimulation of theproliferation of 4MBr-5 cells (monkey epithelial cell line).
• OfficialSymbol: FGF7

Gene Information

• Gene Name: FGF7 fibroblast growth factor 7[ Homo sapiens ]
• Synonyms: FGF7; fibroblastgrowth factor 7; KGF; HBGF-7;keratinocyte growth factor; FGF-7; OTTHUMP00000162252; heparin-binding growthfactor 7
• Gene ID: 2252
• mRNA Refseq: NM_002009
• Protein Refseq: NP_002000
• MIM: 148180
• UniProt ID: P21781
• Chromosome Location: 15q15-q21.1
• Pathway: Downstream signalingof activated FGFR; FGFR ligand binding and activation; FGFR2 ligand bindingand activation; FGFR2b ligand binding and activation; FRS2-mediated cascade; Glypican3 network; IRS-mediated signalling; IRS-related events; Insulin receptorsignalling cascade; MAPK signaling pathway; Melanoma; Negative regulation ofFGFR signaling; PI-3K cascade; Pathways in cancer; Phospholipase C-mediated cascade;SHC-mediated cascade
• Function: chemoattractantactivity; growth factor activity; heparin binding; type 2 fibroblast growthfactor receptor binding