Recombinant Human FER, GST-tagged

• Cat.No.: FER-2611H
• Product Overview: Recombinant Full-length of human FER (1-822(end) amino acids) was expressed as N terminal GST-fusion protein (122 kDa) usingbaculovirusexpression system. GST-FER was purified by using glutathione sepharose chromatography and anion exchange chromatography.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Description: Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.
• Purity: 94 %. The purity was assessed by SDS-PAGE/CBB staining.
• Storage Buffer: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5.
• ATP: 100mM.
• Substrate: Srctide.
• Storage: Store at -80℃. Avoid repeating freeze-thaws.

Gene Information

• Gene Name: FER fer (fps/fes related) tyrosine kinase [ Homo sapiens ]
• Synonyms: FER; fer (fps/fes related) tyrosine kinase; TYK3; tyrosine-protein kinase Fer; p94-Fer; tyrosine kinase 3; phosphoprotein NCP94; proto-oncogene c-Fer; EC 2.7.10.2
• Gene ID: 2241
• mRNA Refseq: NM_005246
• Protein Refseq: NP_005237
• MIM: 176942
• UniProt ID: P16591
• Chromosome Location: 5q21
• Pathway: Adherens junction
• Function: ATP binding; Rab GTPase binding; actin binding; cadherin binding; gamma-catenin binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein kinase binding; protein tyrosine kinase activity; transferase activity