Recombinant Human FDFT1
| Cat.No. : | FDFT1-27574TH |
| Product Overview : | Recombinant full length Human FDFT1 with an N-terminal proprietary tag; 71.98 kDa. |
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| Description : | This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. |
| Protein length : | 417 amino acids |
| Molecular Weight : | 71.980kDa inclusive of tags |
| Source : | Wheat germ |
| Form : | Liquid |
| Purity : | Proprietary Purification |
| Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : | MEFVKCLGHPEEFYNLVRFRVGGKRKVMPKMDQDSLSSSL KTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALD TLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDK HVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGED TERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRL RNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQ AVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQY LTTLSQVTEDYVQTGEH |
| Sequence Similarities : | Belongs to the phytoene/squalene synthase family. |
| Tag : | Non |
| Gene Name | FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Homo sapiens ] |
| Official Symbol | FDFT1 |
| Synonyms | FDFT1; farnesyl-diphosphate farnesyltransferase 1; squalene synthase; |
| Gene ID | 2222 |
| mRNA Refseq | NM_004462 |
| Protein Refseq | NP_004453 |
| MIM | 184420 |
| Uniprot ID | P37268 |
| Chromosome Location | 8p23.1-p22 |
| Pathway | Cholesterol Biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, FPP => cholesterol, organism-specific biosystem; Cholesterol biosynthesis, FPP => |
| Function | farnesyl-diphosphate farnesyltransferase activity; oxidoreductase activity; squalene synthase activity; transferase activity, transferring alkyl or aryl (other than methyl) groups; |
Not For Human Consumption!
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