Recombinant Human FDFT1
Cat.No. : | FDFT1-27574TH |
Product Overview : | Recombinant full length Human FDFT1 with an N-terminal proprietary tag; 71.98 kDa. |
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Species : | Human |
Source : | Wheat Germ |
Tag : | Non |
Protein Length : | 417 amino acids |
Description : | This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. |
Molecular Weight : | 71.980kDa inclusive of tags |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MEFVKCLGHPEEFYNLVRFRVGGKRKVMPKMDQDSLSSSL KTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALD TLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDK HVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGED TERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRL RNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQ AVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQY LTTLSQVTEDYVQTGEH |
Sequence Similarities : | Belongs to the phytoene/squalene synthase family. |
Gene Name | FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Homo sapiens ] |
Official Symbol | FDFT1 |
Synonyms | FDFT1; farnesyl-diphosphate farnesyltransferase 1; squalene synthase; |
Gene ID | 2222 |
mRNA Refseq | NM_004462 |
Protein Refseq | NP_004453 |
MIM | 184420 |
Uniprot ID | P37268 |
Chromosome Location | 8p23.1-p22 |
Pathway | Cholesterol Biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, FPP => cholesterol, organism-specific biosystem; Cholesterol biosynthesis, FPP => |
Function | farnesyl-diphosphate farnesyltransferase activity; oxidoreductase activity; squalene synthase activity; transferase activity, transferring alkyl or aryl (other than methyl) groups; |
◆ Recombinant Proteins | ||
FDFT1-1048HFL | Recombinant Full Length Human FDFT1 Protein, C-Flag-tagged | +Inquiry |
FDFT1-1829H | Recombinant Human FDFT1 protein, His-tagged | +Inquiry |
RFL4907BF | Recombinant Full Length Bovine Squalene Synthase(Fdft1) Protein, His-Tagged | +Inquiry |
FDFT1-3354C | Recombinant Chicken FDFT1 | +Inquiry |
FDFT1-5803M | Recombinant Mouse FDFT1 Protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
FDFT1-6271HCL | Recombinant Human FDFT1 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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