Recombinant Human FBXL8, His-tagged

• Cat.No.: FBXL8-12782H
• Product Overview: Recombinant Human FBXL8 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-374a.a.
• Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FBXL8 F-box and leucine-rich repeat protein 8 [ Homo sapiens ]
• Official Symbol: FBXL8
• Synonyms: FBXL8; F-box and leucine-rich repeat protein 8; F-box/LRR-repeat protein 8; Fbl8; F-box protein FBL8; FBL8; FLJ11278; MGC19959
• Gene ID: 55336
• mRNA Refseq: NM_018378
• Protein Refseq: NP_060848
• MIM: 609077
• UniProt ID: Q96CD0
• Chromosome Location: 16q22.1-q22.3
• Function: protein binding