Recombinant Human FBLIM1 Protein, GST-tagged

• Cat.No.: FBLIM1-3870H
• Product Overview: Human FBLIM1 full-length ORF (BAB55115.1, 1 a.a. - 276 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 57.2 kDa
• AA Sequence: MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGDICAFYHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FBLIM1 filamin binding LIM protein 1 [ Homo sapiens ]
• Official Symbol: FBLIM1
• Synonyms: FBLIM1; filamin binding LIM protein 1; filamin-binding LIM protein 1; CAL; FBLP 1; migfilin; CSX-associated LIM; MIG2-interacting protein; filamin-binding LIM protein-1; mitogen-inducible 2 interacting protein; mitogen-inducible 2-interacting protein; FBLP1; FBLP-1; RP11-169K16.5; DKFZp434G171
• Gene ID: 54751
• mRNA Refseq: NM_001024215
• Protein Refseq: NP_001019386
• MIM: 607747
• UniProt ID: Q8WUP2