Recombinant Human FARSB, His-tagged

• Cat.No.: FARSB-12750H
• Product Overview: Recombinant Human FARSB protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 240-589a.a.
• Description: This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FARSB phenylalanyl-tRNA synthetase, beta subunit [ Homo sapiens ]
• Official Symbol: FARSB
• Synonyms: FARSB; phenylalanyl-tRNA synthetase, beta subunit; FARSLB, phenylalanyl tRNA synthetase like, beta subunit; phenylalanine--tRNA ligase beta subunit; FRSB; PheHB; phenylalanine tRNA ligase 1; beta; cytoplasmic; phenylalanine-tRNA ligase beta chain; phenylalanine--tRNA ligase beta chain; phenylalanyl-tRNA synthetase beta chain; phenylalanyl-tRNA synthetase beta-subunit; phenylalanine tRNA ligase 1, beta, cytoplasmic; phenylalanyl-tRNA synthetase-like, beta subunit; phenylalanine-tRNA synthetase-like, beta subunit; PheRS; FARSLB; HSPC173
• Gene ID: 10056
• mRNA Refseq: NM_005687
• Protein Refseq: NP_005678
• MIM: 609690
• UniProt ID: Q9NSD9
• Chromosome Location: 2q36.2
• Pathway: Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Cytosolic tRNA aminoacylation, organism-specific biosystem; Gene Expression, organism-specific biosystem; tRNA Aminoacylation, organism-specific biosystem
• Function: ATP binding; RNA binding; ligase activity; magnesium ion binding; nucleotide binding; phenylalanine-tRNA ligase activity