Recombinant Human FAM84A, His-tagged

• Cat.No.: FAM84A-15868H
• Product Overview: Recombinant human FAM84A protein, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: FAM84A belongs to the FAM84 family of proteins and is predominantly expressed in testis. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. FAM84A is up-regulated in colorectal cancer lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 34.9kDa (315aa), confirmed by MALDI-TOF
• Protein length: 1-292aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGNQLDR ITHLNYSELP TGDPSGIEKD ELRVGVAYFF SDDEEDLDER GQPDKFGVKA PPGCTPCPES PSRHHHHLLH QLVLNETQFS AFRGQECIFS KVSGGPQGAD LSVYAVTALP ALCEPGDLLE LLWLQPAPEP PAPAPHWAVY VGGGQIIHLH QGEIRQDSLY EAGAANVGRV VNSWYRYRPL VAELVVQNAC GHLGLKSEEI CWTNSESFAA WCRFGKREFK AGGEVPAGTQ PPQQQYYLKV HLGENKVHTA RFHSLEDLIR EKRRIDASGR LRVLQELADL VDDKE
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: FAM84A family with sequence similarity 84, member A [ Homo sapiens ]
• Official Symbol: FAM84A
• Synonyms: FAM84A; family with sequence similarity 84, member A; protein FAM84A; FLJ35392; neurological/sensory 1; NSE1; neurologic sensory protein 1; PP11517
• Gene ID: 151354
• mRNA Refseq: NM_145175
• Protein Refseq: NP_660158
• MIM: 611234
• UniProt ID: Q96KN4
• Chromosome Location: 2p24.3