Recombinant Human FAM49B, His-tagged

• Cat.No.: FAM49B-7589H
• Product Overview: Recombinant human FAM49B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Antigen Description: FAM49B has been provisionally designated FAM49B pending further characterization. In a recent genome-wide transcriptional analysis, It identified a gene signature for multiple sclerosis (MS), which reverted back to normal during pregnancy. Reversion was particularly evident for 7 genes: SOCS2, TNFAIP3, NR4A2, CXCR4, POLR2J, FAM49B, and STAG3L1, most of which encode negative regulators of inflammation.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl, 1mM DTT
• Molecular Mass: 39.1 kDa(347aa) confirmed by MALDI-TOF
• Protein length: 1-324aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGNLLKV LTCTDLEQGP NFFLDFENAQ PTESEKEIYN QVNVVLKDAE GILEDLQSYR GAGHEIREAI QHPADEKLQE KAWGAVVPLV GKLKKFYEFS QRLEAALRGL LGALTSTPYS PTQHLEREQA LAKQFAEILH FTLRFDELKM TNPAIQNDFS YYRRTLSRMR INNVPAEGEN EVNNELANRM SLFYAEATPM LKTLSDATTK FVSENKNLPI ENTTDCLSTM ASVCRVMLET PEYRSRFTNE ETVSFCLRVM VGVIILYDHV HPVGAFAKTS KIDMKGCIKV LKDQPPNSVE GLLNALRYTT KHLNDETTSK QIKSMLQ
• Purity: >90% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml

Gene Information

• Gene Name: FAM49B?family with sequence similarity 49, member B [?Homo sapiens?]
• Official Symbol: FAM49B
• Synonyms: FAM49B; L1; BM-009; protein FAM49B; family with sequence similarity 49, member B
• Gene ID: 51571
• mRNA Refseq: NM_001256763
• Protein Refseq: NP_001243692
• UniProt ID: Q9NUQ9
• Chromosome Location: 8q24.21