Recombinant Human EXOC3, GST-tagged

• Cat.No.: EXOC3-12586H
• Product Overview: Recombinant Human EXOC3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 381-745a.a.
• Description: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: EXOC3 exocyst complex component 3 [ Homo sapiens ]
• Official Symbol: EXOC3
• Synonyms: EXOC3; exocyst complex component 3; SEC6 like 1 (S. cerevisiae) , SEC6L1; Sec6p; SEC6-like 1; Sec 6 homolog; exocyst complex component Sec6; SEC6; SEC6L1
• Gene ID: 11336
• mRNA Refseq: NM_007277
• Protein Refseq: NP_009208
• MIM: 608186
• UniProt ID: O60645
• Chromosome Location: 5p15.33
• Pathway: Arf6 trafficking events, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Insulin Pathway, organism-specific biosystem; Insulin Synthesis and Processing, organism-specific biosystem; Stabilization and expansion of the E-cadherin adherens junction, organism-specific biosystem; Tight junction, organism-specific biosystem
• Function: protein binding