Recombinant Human EPSTI1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: EPSTI1-6381H
• Product Overview: EPSTI1 MS Standard C13 and N15-labeled recombinant protein (NP_001002264) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene has been shown to promote tumor invasion and metastasis in some invasive cancer cells when overexpressed. Expression of this gene has been shown to be upregulated by direct binding of the Kruppel like factor 8 protein to promoter sequences. The translated protein interacts with the amino terminal region of the valosin containing protein gene product, resulting in the nuclear translocation of the nuclear factor kappa B subunit 1 gene product, and activation of target genes. Overexpression of this gene has been observed in some breast cancers and in some individuals with systemic lupus erythematosus (SLE).
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 47.5 kDa
• AA Sequence: MNTRNRVVNSGLGASPASRPTRDPQ DPSGRQGELSPVEDQREGLEAAPKG PSRESVVHAGQRRTSAYTLIAPNIN RRNEIQRIAEQELANLEKWKEQNRA KPVHLVPRRLGGSQSETEVRQKQQL QLMQSKYKQKLKREESVRIKKEAEE AELQKMKAIQREKSNKLEEKKRLQE NLRREAFREHQQYKTAEFLSKLNTE SPDRSACQSAVCGPQSSTWKLPILP RDHSWARSWAYRDSLKAEENRKLQK MKDEQHQKSELLELKRQQQEQERAK IHQTEHRRVNNAFLDRLQGKSQPGG LEQSGGCWNMNSGNSWGSLLVFSRH LRVYEKILTPIWPSSTDLEKPHEML FLNVILFSLTVFTLISTAHTLDRAV RSDWLLLVLIYACLEELIPELIFNL YCQGNATLFFTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EPSTI1 epithelial stromal interaction 1 [ Homo sapiens (human) ]
• Official Symbol: EPSTI1
• Synonyms: EPSTI1; epithelial stromal interaction 1 (breast); epithelial-stromal interaction protein 1; BRESI1; epithelial stromal interaction protein 1; MGC29634
• Gene ID: 94240
• mRNA Refseq: NM_001002264
• Protein Refseq: NP_001002264
• MIM: 607441
• UniProt ID: Q96J88