Recombinant Human EPHB4, GST-tagged
Cat.No. : | EPHB4-12495H |
Product Overview : | Recombinant Human EPHB4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Availability | March 15, 2025 |
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Species : | Human |
Source : | E.coli |
Tag : | GST |
Protein Length : | 639-987a.a. |
Description : | Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name | EPHB4 EPH receptor B4 [ Homo sapiens ] |
Official Symbol | EPHB4 |
Synonyms | EPHB4; EPH receptor B4; EphB4 , HTK; ephrin type-B receptor 4; Tyro11; ephrin receptor EphB4; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; hepatoma transmembrane kinase; tyrosine-protein kinase TYRO11; tyrosine-protein kinase receptor HTK; HTK; MYK1; TYRO11; |
Gene ID | 2050 |
mRNA Refseq | NM_004444 |
Protein Refseq | NP_004435 |
MIM | 600011 |
UniProt ID | P54760 |
Chromosome Location | 7q22 |
Pathway | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; EPHB forward signaling, organism-specific biosystem; Ephrin B reverse signaling, organism-specific biosystem; EphrinB-EPHB pathway, organism-specific biosystem; |
Function | ATP binding; ephrin receptor activity; ephrin receptor activity; nucleotide binding; protein binding; protein tyrosine kinase activity; receptor activity; transmembrane receptor protein tyrosine kinase activity; |
◆ Recombinant Proteins | ||
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EPHB4-231H | Recombinant Human EPHB4, C13&N15-labeled | +Inquiry |
EPHB4-853H | Recombinant Human EPHB4 Protein, His (Fc)-Avi-tagged | +Inquiry |
EPHB4-1898H | Recombinant Human EPHB4 Protein, MYC/DDK-tagged | +Inquiry |
EPHB4-4943H | Recombinant Human EPHB4 Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Cell & Tissue Lysates | ||
EPHB4-001HCL | Recombinant Human EPHB4 cell lysate | +Inquiry |
EPHB4-2128MCL | Recombinant Mouse EPHB4 cell lysate | +Inquiry |
EPHB4-2970HCL | Recombinant Human EPHB4 cell lysate | +Inquiry |
Not For Human Consumption!
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