Recombinant Human EPHA3
Cat.No. : | EPHA3-26440TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 571-983 of Human Eph receptor A3 with N-terminal proprietary tag, expressed in a Baculovirus infected Sf9 cell expression system, 72kDa. |
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Species : | Human |
Tag : | Non |
Protein Length : | 571-983 a.a. |
Description : | This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. |
Biological activity : | Specific activity of Eph receptor A3 was determined to be 102 nmol/min/mg as per activity assay protocol. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Gene Name | EPHA3 EPH receptor A3 [ Homo sapiens ] |
Official Symbol | EPHA3 |
Synonyms | EPHA3; EPH receptor A3; EphA3 , ETK, ETK1, TYRO4; ephrin type-A receptor 3; HEK; HEK4; |
Gene ID | 2042 |
mRNA Refseq | NM_005233 |
Protein Refseq | NP_005224 |
MIM | 179611 |
Uniprot ID | P29320 |
Chromosome Location | 3p11.2 |
Pathway | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; EPHA forward signaling, organism-specific biosystem; EphrinA-EPHA pathway, organism-specific biosystem; |
Function | ATP binding; GPI-linked ephrin receptor activity; nucleotide binding; protein binding; receptor activity; |
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◆ Cell & Tissue Lysates | ||
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EPHA3-002MCL | Recombinant Mouse EPHA3 cell lysate | +Inquiry |
Not For Human Consumption!
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