Recombinant Human ENPP2, GST-tagged

• Cat.No.: ENPP2-6998H
• Product Overview: Recombinant human ENPP2 (36-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5 end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids which evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. It also may induce parturition. ENPP2 stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas.
• Source: Sf9 Cells
• Species: Human
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~126 kDa
• Protein length: 36 aa-end
• Purity: >70%
• Applications: Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.05 μg/μl

Gene Information

• Gene Name: ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 [ Homo sapiens ]
• Official Symbol: ENPP2
• Synonyms: ENPP2; ectonucleotide pyrophosphatase/phosphodiesterase 2; PDNP2; ectonucleotide pyrophosphatase/phosphodiesterase family member 2; ATX; autotaxin; PD IALPHA; E-NPP 2; autotaxin-t; plasma lysophospholipase D; extracellular lysophospholipase D; phosphodiesterase I/nucleotide pyrophosphatase 2; NPP2; ATX-X; LysoPLD; AUTOTAXIN; PD-IALPHA; FLJ26803
• Gene ID: 5168
• mRNA Refseq: NM_001040092
• Protein Refseq: NP_001035181
• MIM: 601060
• UniProt ID: Q13822
• Chromosome Location: 8q24.1
• Pathway: Ether lipid metabolism, organism-specific biosystem; Ether lipid metabolism, conserved biosystem
• Function: alkylglycerophosphoethanolamine phosphodiesterase activity; calcium ion binding; hydrolase activity; lysophospholipase activity; nucleic acid binding; nucleotide diphosphatase activity; phosphodiesterase I activity; polysaccharide binding; scavenger receptor activity; transcription factor binding; zinc ion binding