Recombinant Human EMX2 Protein, GST-tagged

• Cat.No.: EMX2-3296H
• Product Overview: Human EMX2 full-length ORF ( NP_004089.1, 1 a.a. - 252 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.[provided by RefSeq, Sep 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 54.12 kDa
• AA Sequence: MFQPAPKRCFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAGRGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EMX2 empty spiracles homeobox 2 [ Homo sapiens ]
• Official Symbol: EMX2
• Synonyms: EMX2; empty spiracles homeobox 2; empty spiracles homolog 2 (Drosophila); homeobox protein EMX2; empty spiracles homolog 2; empty spiracles-like protein 2
• Gene ID: 2018
• mRNA Refseq: NM_001165924
• Protein Refseq: NP_001159396
• MIM: 600035
• UniProt ID: Q04743