Recombinant Human ELK1, C-MYC-tagged

• Cat.No.: ELK1-27228TH
• Product Overview: Recombinant fragment, corresponding to amino acids 307-428 of Human ELK1, a maltose binding protein fusion protein with an amino-terminal polyhistidine tag and a c-terminal myc tag , 60 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Myc
• ProteinLength: 307-428 a.a.
• Description: This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Conjugation: c-myc
• Tissue specificity: Lung and testis.
• Form: Lyophilised:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute lyophilized in distilled water to a concentration of 0.2-1.0 mg/mL.
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: None
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the ETS family.Contains 1 ETS DNA-binding domain.

Gene Information

• Gene Name: ELK1 ELK1, member of ETS oncogene family [ Homo sapiens ]
• Official Symbol: ELK1
• Synonyms: ELK1; ELK1, member of ETS oncogene family; ETS domain-containing protein Elk-1
• Gene ID: 2002
• mRNA Refseq: NM_001114123
• Protein Refseq: NP_001107595
• MIM: 311040
• Uniprot ID: P19419
• Chromosome Location: Xp11.23
• Pathway: Activated TLR4 signalling, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem
• Function: protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity