Recombinant Human EIF3K, His-tagged

• Cat.No.: EIF3K-3482H
• Product Overview: Recombinant human EIF3K protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: EIF3K, also known as eukaryotic translation initiation factor 3 subunit K, belongs to the eIF3 subunit K family. It is the smallest subunit of eIF3 and it interacts with several other subunits of eIF3 and the 40S ribosomal subunit. This protein is conserved among high eukaryotes, including mammals, insects, and plants, and it is ubiquitously expressed in human tissues. It is distributed both in nucleus and cytoplasm and colocalizes with cyclin D3, a regulatory subunit of cyclin-dependent kinase 4 (Cdk4).
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
• Molecular Weight: 27.2 kDa (238aa) confirmed by MALDI-TOF
• Purity: > 95% by SDS - PAGE
• Concentration: 1.0 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAMFEQMRAN VGKLLKGIDR YNPENLATLE RYVETQAKEN AYDLEANLAV LKLYQFNPAF FQTTVTAQIL LKALTNLPHT DFTLCKCMID QAHQEERPIR QILYLGDLLE TCHFQAFWQA LDENMDLLEG ITGFEDSVRK FICHVVGITY QHIDRWLLAE MLGDLSDSQL KVWMSKYGWS ADESGQIFIC SQEESIKPKN IVEKIDFDSV SSIMASSQ
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: EIF3K eukaryotic translation initiation factor 3, subunit K [ Homo sapiens ]
• Synonyms: eukaryotic translation initiation factor 3, subunit K; M9; ARG134; PLAC24; PTD001; EIF3S12; HSPC029; MSTP001; PLAC-24; PRO1474; EIF3-p28; EIF3K; eIF-3 p25; eIF-3 p28; muscle specific; muscle-specific gene M9 protein; eukaryotic translation initiation factor 3 subunit 12; eukaryotic translation initiation factor 3, subunit 12
• Gene ID: 27335
• mRNA Refseq: NM_013234
• Protein Refseq: NP_037366
• MIM: 609596
• UniProt ID: Q9UBQ5
• Chromosome Location: 19q13.2
• Pathway: Metabolism of proteins; Gene Expression
• Function: protein binding; ribosome binding; contributes to translation initiation factor activity