Recombinant Human EEF2K
Cat.No. : | EEF2K-27779TH |
Product Overview : | Recombinant full length human EEF2K with N-terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system; amino acids 1-725, 125kDa. |
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Species : | Human |
Tag : | Non |
Protein Length : | 1-725 a.a. |
Description : | This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. |
Biological activity : | Specific activity of EEF2K was determined to be 50nmol/min/mg as per activity assay protocol |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. Alpha-type protein kinase family.Contains 1 alpha-type protein kinase domain. |
Full Length : | Full L. |
Gene Name | EEF2K eukaryotic elongation factor-2 kinase [ Homo sapiens ] |
Official Symbol | EEF2K |
Synonyms | EEF2K; eukaryotic elongation factor-2 kinase; eukaryotic elongation factor 2 kinase; eEF 2K; |
Gene ID | 29904 |
mRNA Refseq | NM_013302 |
Protein Refseq | NP_037434 |
MIM | 606968 |
Uniprot ID | O00418 |
Chromosome Location | 16p12 |
Pathway | IRS-mediated signalling, organism-specific biosystem; IRS-related events, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem; PI3K Cascade, organism-specific biosystem; PKB-mediated events, organism-specific biosystem; |
Function | ATP binding; calcium ion binding; calmodulin binding; elongation factor-2 kinase activity; nucleotide binding; |
◆ Recombinant Proteins | ||
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EEF2K-1270H | Recombinant Human EEF2K Protein (A2-E725), Tag Free | +Inquiry |
EEF2K-1675R | Recombinant Rat EEF2K Protein, His (Fc)-Avi-tagged | +Inquiry |
Eef2k-2739M | Recombinant Mouse Eef2k Protein, Myc/DDK-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
EEF2K-6711HCL | Recombinant Human EEF2K 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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