Recombinant Human dynactin 6, His-tagged

• Cat.No.: DCTN6-609H
• Product Overview: DCTN6, 1-190aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-190 a.a.
• Description: DCTN6 contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known. Recombinant human DCTN6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Form: Liquid. In Phosphate Buffered Saline (pH7.4) containing 10% glycerol
• Molecular Mass: 23.1kDa (213aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAEKTQK SVKIAPGAVV CVESEIRGDV TIGPRTVIHP KARIIAEAGP IVIGEGNLIE EQALIINAYP DNITPDTEDP EPKPMIIGTN NVFEVGCYSQ AMKMGDNNVI ESKAYVGRNV ILTSGCIIGA CCNLNTFEVI PENTVIYGAD CLRRVQTERP QPQTLQLDFL MKILPNYHHL KKTMKGSSTP VKN
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: DCTN6 dynactin 6 [ Homo sapiens ]
• Official Symbol: DCTN6
• Synonyms: DCTN6; dynactin 6; dynactin subunit 6; WS 3; protein WS-3; dynactin subunit p27; novel RGD-containing protein; WS3; p27; WS-3
• Gene ID: 10671
• mRNA Refseq: NM_006571
• Protein Refseq: NP_006562
• MIM: 612963
• UniProt ID: O00399
• Chromosome Location: 8p12-p11
• Pathway: Vasopressin-regulated water reabsorption, organism-specific biosystem; Vasopressin-regulated water reabsorption, conserved biosystem
• Function: dynein binding; transferase activity