Recombinant Human DPYSL2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DPYSL2-6183H
• Product Overview: DPYSL2 MS Standard C13 and N15-labeled recombinant protein (NP_001377) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 62.3 kDa
• AA Sequence: MSYQGKKNIPRITSDRLLIKGGKIV NDDQSFYADIYMEDGLIKQIGENLI VPGGVKTIEAHSRMVIPGGIDVHTR FQMPDQGMTSADDFFQGTKAALAGG TTMIIDHVVPEPGTSLLAAFDQWRE WADSKSCCDYSLHVDISEWHKGIQE EMEALVKDHGVNSFLVYMAFKDRFQ LTDCQIYEVLSVIRDIGAIAQVHAE NGDIIAEEQQRILDLGITGPEGHVL SRPEEVEAEAVNRAITIANQTNCPL YITKVMSKSSAEVIAQARKKGTVVY GEPITASLGTDGSHYWSKNWAKAAA FVTSPPLSPDPTTPDFLNSLLSCGD LQVTGSAHCTFNTAQKAVGKDNFTL IPEGTNGTEERMSVIWDKAVVTGKM DENQFVAVTSTNAAKVFNLYPRKGR IAVGSDADLVIWDPDSVKTISAKTH NSSLEYNIFEGMECRGSPLVVISQG KIVLEDGTLHVTEGSGRYIPRKPFP DFVYKRIKARSRLAELRGVPRGLYD GPVCEVSVTPKTVTPASSAKTSPAK QQAPPVRNLHQSGFSLSGAQIDDNI PRRTTQRIVAPPGGRANITSLGTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DPYSL2 dihydropyrimidinase-like 2 [ Homo sapiens (human) ]
• Official Symbol: DPYSL2
• Synonyms: DPYSL2; dihydropyrimidinase-like 2; dihydropyrimidinase-related protein 2; CRMP2; DHPRP2; DRP 2; DRP2; unc-33-like phosphoprotein 2; collapsin response mediator protein hCRMP-2; N2A3; DRP-2; ULIP2; CRMP-2; ULIP-2
• Gene ID: 1808
• mRNA Refseq: NM_001386
• Protein Refseq: NP_001377
• MIM: 602463
• UniProt ID: Q16555