Recombinant Human DLGAP4, His-tagged

• Cat.No.: DLGAP4-26163TH
• Product Overview: Recombinant fragment, corresponding to amino acids 9-453 of Human DLGAP4 isoform 3 with N terminal His tag; 445 amino acids, 60kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 9-453 a.a.
• Description: The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Conjugation: HIS
• Form: Lyophilised:Reconstitute with 152 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: KQCSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQD TYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGG VAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRK LSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSV PSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPN SISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETER LEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKF QQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDI SMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKP AKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL
• Sequence Similarities: Belongs to the SAPAP family.

Gene Information

• Gene Name: DLGAP4 discs, large (Drosophila) homolog-associated protein 4 [ Homo sapiens ]
• Official Symbol: DLGAP4
• Synonyms: DLGAP4; discs, large (Drosophila) homolog-associated protein 4; disks large-associated protein 4; DAP4; KIAA0964; SAPAP4
• Gene ID: 22839
• mRNA Refseq: NM_014902
• Protein Refseq: NP_055717
• Uniprot ID: Q9Y2H0
• Chromosome Location: 20q11.23
• Function: protein binding