Recombinant Human CYP20A1, His-tagged

• Cat.No.: CYP20A1-11767H
• Product Overview: Recombinant Human CYP20A1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 112-462a.a.
• Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 [ Homo sapiens ]
• Official Symbol: CYP20A1
• Synonyms: CYP20A1; cytochrome P450, family 20, subfamily A, polypeptide 1; cytochrome P450 20A1; CYP M; cytochrome P450 monooxygenase; CYP-M; MGC22229
• Gene ID: 57404
• mRNA Refseq: NM_177538
• Protein Refseq: NP_803882
• UniProt ID: Q6UW02
• Chromosome Location: 2q33
• Function: electron carrier activity; heme binding; metal ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen