Recombinant Human CXCR1 Protein

• Cat.No.: CXCR1-2176H
• Product Overview: Human CXCR1 full-length ORF (NP_000625.1) recombinant protein without tag.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: Non
• Description: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]
• Form: Liquid
• Molecular Mass: 39.8 kDa
• AA Sequence: MSNITDPQMWDFDDLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: CXCR1 chemokine (C-X-C motif) receptor 1 [ Homo sapiens ]
• Official Symbol: CXCR1
• Synonyms: CXCR1; chemokine (C-X-C motif) receptor 1; CMKAR1, IL8RA, interleukin 8 receptor, alpha; C-X-C chemokine receptor type 1; CD181; CDw128a; CKR 1; CXC-R1; CXCR-1; IL-8R A; IL-8 receptor type 1; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A; high affinity interleukin-8 receptor A; C-C; CD128; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; C-C-CKR-1
• Gene ID: 3577
• mRNA Refseq: NM_000634
• Protein Refseq: NP_000625
• MIM: 146929
• UniProt ID: P25024