Recombinant Human CSH2 Protein, His-tagged

• Cat.No.: CSH2-193H
• Product Overview: Recombinant Human CSH2, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity.
• Form: 50mM Tris, 8M Urea, pH8.0.
• Molecular Mass: 18.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CSH2 chorionic somatomammotropin hormone 2 [ Homo sapiens ]
• Official Symbol: CSH2
• Synonyms: CSB; CS-2; hCS-B
• Gene ID: 1443
• mRNA Refseq: NM_022645.2
• Protein Refseq: NP_072171.1
• MIM: 118820
• UniProt ID: P01243