Recombinant Human CNTN1, Fc-tagged

• Cat.No.: CNTN1-166H
• Product Overview: Human contactin-1 (aa 1-993) is fused at the C-terminus to the Fc portion of human IgG.

Specification

• Description: Contactin-1 is a member of the contactins, which mediate cell surface interactions during nervous system development. It is involved in oligodendrocytes generation by acting as a ligand of Notch1. It is also involved in motor coordination.
• Source: HEK293 Cells
• Species: Human
• Tag: Fc
• Form: Liquid. 0.2μm-filtered solution in PBS.
• Molecular Mass: ~120kDa (SDS-PAGE)
• Purity: ≥90% (SDS-PAGE)
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
• Protein length: 1-993 a.a.

Gene Information

• Gene Name: CNTN1 contactin 1 [ Homo sapiens ]
• Official Symbol: CNTN1
• Synonyms: CNTN1; contactin 1; contactin-1; F3; glycoprotein gP135; GP135; neural cell surface protein F3
• Gene ID: 1272
• mRNA Refseq: NM_001256063
• Protein Refseq: NP_001242992
• MIM: 600016
• UniProt ID: Q12860
• Chromosome Location: 12q11-q12
• Pathway: Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Axon guidance, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Developmental Biology, organism-specific biosystem; L1CAM interactions, organism-specific biosystem