Recombinant Human CNPY3, His-tagged

• Cat.No.: CNPY3-7550H
• Product Overview: Recombinant human CNPY3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: 31-278aa
• Antigen Description: Canopy 3 homolog, also known as CNPY3, is Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. This protein is required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, CNPY3i s required for both innate and adaptive immune responses.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 29.9 kDa (271aa) confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSGPSQAGA EENDWVRLPS KCEVCKYVAV ELKSAFEETG KTKEVIGTGY GILDQKASGV KYTKSDLRLI EVTETICKRL LDYSLHKERT GSNRFAKGMS ETFETLHNLV HKGVKVVMDI PYELWNETSA EVADLKKQCD VLVEEFEEVI EDWYRNHQEE DLTEFLCANH VLKGKDTSCL AEQWSGKKGD TAALGGKKSK KKSSRAKAAG GRSSSSKQRK ELGGLEGDPS PEEDEGIQKA SPLTHSPPDE L
• Purity: >85% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: CNPY3 canopy 3 homolog (zebrafish) [ Homo sapiens ]
• Official Symbol: CNPY3
• Synonyms: CNPY3; canopy 3 homolog (zebrafish); TNRC5, trinucleotide repeat containing 5; protein canopy homolog 3; CAG4A; CAG repeat containing; CTG repeat protein 4a; protein associated with TLR4; expanded repeat domain, CAG/CTG 5; trinucleotide repeat containing 5; expanded repeat-domain protein CAG/CTG 5; protein associated with Toll-like receptor 4A; trinucleotide repeat-containing gene 5 protein; ERDA5; TNRC5; PRAT4A
• Gene ID: 10695
• mRNA Refseq: NM_006586
• Protein Refseq: NP_006577
• MIM: 610774
• UniProt ID: Q9BT09
• Chromosome Location: 6pter-p12.1
• Pathway: Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Toll Receptor Cascades, organism-specific biosystem; Trafficking and processing of endosomal TLR, organism-specific biosystem
• Function: receptor binding