Recombinant Human CNOT11 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CNOT11-820H
• Product Overview: C2orf29 MS Standard C13 and N15-labeled recombinant protein (NP_060016) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 55.2 kDa
• AA Sequence: MPGGGASAASGRLLTAAEQRGSREAAGSASRSGFGGSGGGRGGASGPGSGSGGPGGPAGRMSLTPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPPRELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDPDSSNSGFDSSVASQITEALVSGPKPPIESHFRPEFIRPPPPLHICEDELAWLNPTEPDHAIQWDKSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGETPSETEMSKTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CNOT11 CCR4-NOT transcription complex subunit 11 [ Homo sapiens (human) ]
• Official Symbol: CNOT11
• Synonyms: CNOT11; CCR4-NOT transcription complex subunit 11; C40; C2orf29; CCR4-NOT transcription complex subunit 11; UPF0760 protein C2orf29
• Gene ID: 55571
• mRNA Refseq: NM_017546
• Protein Refseq: NP_060016
• UniProt ID: Q9UKZ1