Recombinant Human CNIH2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CNIH2-4500H
• Product Overview: CNIH2 MS Standard C13 and N15-labeled recombinant protein (NP_872359) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 18.8 kDa
• AA Sequence: MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSFTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CNIH2 cornichon family AMPA receptor auxiliary protein 2 [ Homo sapiens (human) ]
• Official Symbol: CNIH2
• Synonyms: CNIH2; cornichon family AMPA receptor auxiliary protein 2; Cnil; CNIH-2; protein cornichon homolog 2; cornichon homolog 2
• Gene ID: 254263
• mRNA Refseq: NM_182553
• Protein Refseq: NP_872359
• MIM: 611288
• UniProt ID: Q6PI25