Recombinant Human CNBP, His-tagged

• Cat.No.: CNBP-7534H
• Product Overview: Recombinant human CNBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Antigen Description: CNBP is a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. It functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing 0.2M NaCl, 20% glycerol, 1mM DTT.
• Molecular Mass: 21 kDa (193aa) confirmed by MALDI-TOF
• Protein length: 1-170aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSSNECF KCGRSGHWAR ECPTGGGRGR GMRSRGRGFQ FVSSSLPDIC YRCGESGHLA KDCDLQEDAC YNCGRGGHIA KDCKEPKRER EQCCYNCGKP GHLARDCDHA DEQKCYSCGE FGHIQKDCTK VKCYRCGETG HVAINCSKTS EVNCYRCGES GHLARECTIE ATA
• Purity: >90% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: CNBP CCHC-type zinc finger, nucleic acid binding protein [ Homo sapiens ]
• Official Symbol: CNBP
• Synonyms: CNBP; CCHC-type zinc finger, nucleic acid binding protein; DM2, zinc finger protein 9 , zinc finger protein 9 (a cellular retroviral nucleic acid binding protein) , ZNF9; cellular nucleic acid-binding protein; CNBP1; RNF163; ZCCHC22; zinc finger protein 273; erythroid differentiation-related; cellular nucleic acid binding protein; sterol regulatory element-binding protein; zinc finger protein 9 (a cellular retroviral nucleic acid binding protein); DM2; ZNF9; PROMM; FLJ11631
• Gene ID: 7555
• mRNA Refseq: NM_001127192
• Protein Refseq: NP_001120664
• MIM: 116955
• UniProt ID: P62633
• Chromosome Location: 3q21
• Function: DNA binding; metal ion binding; nucleic acid binding; sequence-specific DNA binding transcription factor activity; zinc ion binding