Recombinant Human CMPK1, His-tagged

• Cat.No.: CMPK1-31668TH
• Product Overview: Recombinant full length Human UMP/CMP kinase with an N terminal His tag; 248 amino acids including tag, predicted MWt: 28kDa.

Specification

• Description: Uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. These nucleoside diphosphates are required for cellular nucleic acid synthesis (Liou et al.
• Protein length: 228 amino acids
• Conjugation: HIS
• Molecular Weight: 28.000kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Ubiquitously expressed.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, 1mM DTT, pH 8.0
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MLSRCRSGLL HVLGLSFLLQ TRRPILLCSP RLMKPLVVFV LGGPGAGKGT QCARIVEKYG YTHLSAGELL RDERKNPDSQ YGELIEKYIK EGKIVPVEIT ISLLKREMDQ TMAANAQKNK FLIDGFPRNQ DNLQGWNKTM DGKADVSFVL FFDCNNEICI ERCLERGKSS GRSDDNRESL EKRIQTYLQS TKPIIDLYEE MGKVKKIDAS KSVDEVFDEV VQIFDKEG
• Sequence Similarities: Belongs to the adenylate kinase family.

Gene Information

• Gene Name: CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic [ Homo sapiens ]
• Official Symbol: CMPK1
• Synonyms: CMPK1; cytidine monophosphate (UMP-CMP) kinase 1, cytosolic; CMPK, cytidylate kinase; UMP-CMP kinase; Cytidine monophosphate kinase; UMP CMP kinase; UMP CMPK
• Gene ID: 51727
• mRNA Refseq: NM_001136140
• Protein Refseq: NP_001129612
• MIM: 191710
• Uniprot ID: P30085
• Chromosome Location: 1p34.1-p33
• Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem
• Function: ATP binding; cytidylate kinase activity; nucleotide binding; phosphotransferase activity, phosphate group as acceptor; transferase activity