Recombinant Human CLTRN Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CLTRN-5431H
• Product Overview: TMEM27 MS Standard C13 and N15-labeled recombinant protein (NP_065716) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 25.2 kDa
• AA Sequence: MLWLLFFLVTAIHAELCQPGAENAFKVRLSIRTALGDKAYAWDTNEEYLFKAMVAFSMRKVPNREATEISHVLLCNVTQRVSFWFVVTDPSKNHTLPAVEVQSAIRMNKNRINNAFFLNDQTLEFLKIPSTLAPPMDPSVPIWIIIFGVIFCIIIVAIALLILSGIWQRRRKNKEPSEVDDAEDKCENMITIENGIPSDPLDMKGGHINDAFMTEDERLTPLTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CLTRN collectrin, amino acid transport regulator [ Homo sapiens (human) ]
• Official Symbol: CLTRN
• Synonyms: CLTRN; collectrin, amino acid transport regulator; NX17; NX-17; TMEM27; collectrin; kidney-specific membrane protein; transmembrane protein 27
• Gene ID: 57393
• mRNA Refseq: NM_020665
• Protein Refseq: NP_065716
• MIM: 300631
• UniProt ID: Q9HBJ8