Recombinant Human CLTB, GST-tagged

• Cat.No.: CLTB-11354H
• Product Overview: Recombinant Human CLTB protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-211a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CLTB clathrin, light chain B [ Homo sapiens ]
• Official Symbol: CLTB
• Synonyms: CLTB; clathrin, light chain B; clathrin, light polypeptide (Lcb); clathrin light chain B; Lcb; clathrin, light chain (Lcb); LCB
• Gene ID: 1212
• mRNA Refseq: NM_001834
• Protein Refseq: NP_001825
• MIM: 118970
• UniProt ID: P09497
• Chromosome Location: 5q35.2
• Pathway: Arf1 pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem
• Function: peptide binding; protein binding; structural molecule activity