Recombinant Human CITED2, His-tagged

Description :	The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of HIF1a to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Three transcript variants encoding the same protein have been found for this gene.
Conjugation :	HIS
Source :	E. coli
Form :	Liquid
Purity :	>90% by SDS-PAGE
Storage buffer :	Preservative: NoneConstituents: 50% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8
Storage :	Store at +4°C.
Sequences of amino acids :	MADHMMAMNH GRFPDGTNGL HHHPAHRMGM GQFPSPHHHQ QQQPQHAFNA LMGEHIHYGA GNMNATSGIR HAMGPGTVNG GHPPSALAPA ARFNNSQFMG PPVASQGGSL PASMQLQKLN NQYFNHHPYP HNHYMPDLHP AAGHQMNGTN QHFRDCNPKH SGGSSTPGGS GGSSTPGGSG SSSGGGAGSS NSGGGSGSGN MPASVAHVPA AMLPPNVIDT DFIDEEVLMS LVIEMGLDRI KELPELWLGQ NEFDFMTDFV CKQQPSRVSC LEHHHHHH
Sequence Similarities :	Belongs to the CITED family.
Protein length :	1-270 a.a.
Full Length :	Full L.

Gene Name	CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 [ Homo sapiens ]
Official Symbol	CITED2
Synonyms	CITED2; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; cbp/p300-interacting transactivator 2; MRG1;
Gene ID	10370
mRNA Refseq	NM_001168388
Protein Refseq	NP_001161860
Uniprot ID	Q99967
Chromosome Location	6q23.3
Pathway	HIF-1-alpha transcription factor network, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem;
Function	LBD domain binding; chromatin binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity;