Recombinant Human Chromogranin A (Parathyroid Secretory Protein 1), His-tagged

• Cat.No.: CHGA-033H
• Product Overview: Recombinant human Chromogranin A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Cat. No.: CHGA-033H
• Description: Chromogranin A is a member of the chromogranin/secretogranin (granins) family of neuroendocrine secretory proteins. Chromogranin A (CgA) represents the major soluble protein co-stored and co-released with catecholamines, within chromaffin cells secretory granules. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. It is considered a diagnostic and prognostic marker of several diseases, including a variety of tumours and cardiac heart failure.
• Concentration: 0.5 mg/ml
• Source: Human
• Host: E.coli
• Form: Supplied as a liquid in 20mM MES buffer, pH 6.0, containing 2mM EDTA, 0.1mM PMSF, and 10% glycerol.
• Purity: > 80% by SDS - PAGE
• Sequence: 19-457 amino acids: MGSSHHHHHH SSGLVPRGSH MLPVNSPMNK GDTEVMKCIV EVISDTLSKP SPMPVSQECF ETLRGDERIL SILRHQNLLK ELQDLALQGA KERAHQQKKH SGFEDELSEV LENQSSQAEL KEAVEEPSSK DVMEKREDSK EAEKSGEATD GARPQALPEP MQESKAEGNN QAPGEEEEEE EEATNTHPPA SLPSQKYPGP QAEGDSEGLS QGLV
• Molecular Mass: 51.2 kDa (460aa)
• Applications: SDS-PAGE
• Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: CHGA chromogranin A (parathyroid secretory protein 1) [ Homo sapiens ]
• Official Symbol: CHGA
• Synonyms: CHGA; chromogranin A (parathyroid secretory protein 1); CGA; vasostatin; pancreastatin; parastatin; chromogranin A; parathyroid secretory protein 1; betagranin (N-terminal fragment of chromogranin A); SP-I; Pituitary secretory protein I
• Gene ID: 1113
• mRNA Refseq: NM_001275
• Protein Refseq: NP_001266
• MIM: 118910
• UniProt ID: P10645
• Chromosome Location: 14q32
• Function: calcium ion binding