Recombinant Human CHFR Protein, MYC/DDK-tagged

• Cat.No.: CHFR-3218H
• Product Overview: Recombinant Human CHFR protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 73.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CHFR checkpoint with forkhead and ring finger domains [ Homo sapiens ]
• Official Symbol: CHFR
• Synonyms: RNF116; RNF196
• Gene ID: 56732
• mRNA Refseq: NM_001161344.1
• Protein Refseq: NP_001154816
• MIM: 605209