Recombinant Human chemokine (C-X3-C motif) ligand 1, His-tagged
Cat.No. : | CX3CL1-114H |
Product Overview : | Recombinant human CX3CL1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW=10.9 kDa (97aa). |
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Cat. No. : | CX3CL1-114H |
Product Overview : | Recombinant human CX3CL1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW=10.9 kDa (97aa). |
Description : | CX3CL1, also known as fractalkine. CX3CL1 has a unique CX3C cysteine motif near the amino terminus and is the first member of a fourth branch of the chemokine superfamily. Unlike other known chemokines, CX3CL1 is a type 1 membrane protein containing a chemokine domain tethered on a long mucin like stalk. It is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Also, CX3CL1 elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1. |
Source : | E. Coli. |
Concentration : | 0.5 mg/ml (determined by Bradford assay). |
Form : | Liquid. In Phosphate buffered saline (pH7.4), 10% glycerol. |
Purity : | > 90% by SDS-PAGE. |
Endotoxin Level : | < 1.0 EU per 1 μg of protein (determined by LAL method). |
Amino Acid Sequence : | MGSSHHHHHH SSGLVPRGSH MQHHGVTKCN ITCSKMTSKI PVALLIHYQQ NQASCGKRAI ILETRQHRLF CADPKEQWVK DAMQHLDRQA AALTRNG. |
Storage : | Can be stored at +4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles. |
Gene Name | CX3CL1 chemokine (C-X3-C motif) ligand 1 [ Homo sapiens ] |
Synonyms | CX3CL1; chemokine (C-X3-C motif) ligand 1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin; small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); C-X3-C motif chemokine 1; Neurotactin; Small-inducible cytokine D1; Processed fractalkine |
Gene ID | 6376 |
mRNA Refseq | NM_002996 |
Protein Refseq | NP_002987 |
MIM | 601880 |
UniProt ID | P78423 |
Chromosome Location | 16q13 |
Pathway | Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Signaling by GPCR |
Function | chemokine activity |
Not For Human Consumption!
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