Recombinant Human chemokine (C-X-C motif) ligand 17, His-tagged

• Cat.No.: CXCL17-494H
• Product Overview: CXCL17, 22-119aa Human, His tag, E.coli

Specification

• Description: Chemokine (C-X-C motif) ligand 17, also known as CXCL17, is a small cytokine belonging to the CXC chemokine family. CXCL17 is a 119 amino acid secreted protein that plays a role in angiogenesis. CXCL17 is expressed in skeletal muscle, trachea, lung, intestine and stomach, and is upregulated in duodenal mucosa of patients with acute cholera, as well as breast tumors. CXCL17 is considered a housekeeping chemokine for the movement of immature dendritic cells and non activated blood monocytes into tissues, and is thought to be involved in the innate immune response. Recombinant human CXCL17 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 13.7 kDa (119aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MSSLNPGVAR GHRDRGQASR RWLQEGGQEC ECKDWFLRAP RRKFMTVSGL PKKQCPCDHF KGNVKKTRHQ RHHRKPNKHS RACQQFLKQC QLRSFALPL
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Protein length: 22-119 a.a.

Gene Information

• Gene Name: CXCL17 chemokine (C-X-C motif) ligand 17 [ Homo sapiens ]
• Official Symbol: CXCL17
• Synonyms: CXCL17; chemokine (C-X-C motif) ligand 17; VEGF co-regulated chemokine 1; Dcip1; DMC; UNQ473; VCC1; C-X-C motif chemokine 17; dendritic cell and monocyte chemokine-like protein; VCC-1; MGC138300
• Gene ID: 284340
• mRNA Refseq: NM_198477
• Protein Refseq: NP_940879
• MIM: 611387
• UniProt ID: Q6UXB2
• Chromosome Location: 19q13.2