Recombinant Human CFHR2, His-tagged

• Cat.No.: CFHR2-331H
• Product Overview: Recombinant Human CFHR2 encoding the human CFHR2 (Met1-Lys270) was expressed with a polyhistidine tag at the C-terminus.

Specification

• Cat. No.: CFHR2-331H
• Description: CFHR2 is a member of the complement factor H protein family. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 contains 4 Sushi (CCP/SCR) domains and is expressed by the liver and secreted in plasma. It was identified as novel ligands for both borrelial proteins by employing MALDI-TOF. CFHR2 is synthesized in the liver and secreted into plasma. It may be involved in complement regulation. CFHR2 can also be associated with lipoproteins and may play a role in lipid metabolism.
• Source: Human Cells
• Purity: >(46.1+ 45.6)% as determined by SDS-PAGE
• PredictedN terminal: Glu 19
• MolecularMass: The recombinant protein consists of 263 amino acids and predicts a molecular mass of 30.2 KDa. It migrates as an approximately 31 and 35 KDa band in SDS-PAGE under reducing conditions.
• Formulation: Lyophilized from a 0.2μm filtered solution of PBS, pH 7.4.
• Endotoxin: <1.0 EU per μg of the protein as determined by the LAL method
• Storage: Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: CFHR2
• Tag: Non
• Protein length: 1-270 a.a.

Gene Information

• Gene Name: CFHR2 complement factor H-related 2 [ Homo sapiens ]
• Synonyms: CFHR2; complement factor H-related 2; CFHL2, H factor (complement) like 3 , HFL3; complement factor H-related protein 2; FHR2
• Gene ID: 3080
• mRNA Refseq: NM_005666
• Protein Refseq: NP_005657
• MIM: 600889
• UniProt ID: P36980
• Chromosome Location: 1q31.3