Recombinant Human CEACAM6 protein, His & T7-tagged

• Cat.No.: CEACAM6-8197H
• Product Overview: Recombinant Human CEACAM6 aa. (Lys35~Pro142 (Accession # P40199)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Lys35~Pro142
• Description: This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 15.8kDa.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.5.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: CEACAM6 carcinoembryonic antigen related cell adhesion molecule 6 [ Homo sapiens (human) ]
• Official Symbol: CEACAM6
• Synonyms: CEACAM6; carcinoembryonic antigen related cell adhesion molecule 6; NCA; CEAL; CD66c; carcinoembryonic antigen-related cell adhesion molecule 6; Cluster of Differentiation 66c; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); normal cross-reacting antigen
• Gene ID: 4680
• mRNA Refseq: NM_002483.6
• Protein Refseq: NP_002474.4
• UniProt ID: P40199