Recombinant Human CDK20 protein, GST-tagged

• Cat.No.: CDK20-01H
• Product Overview: Full-length recombinant mouse CDK20 (CCRK) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Description: CDK20 or cyclin-dependent kinase 20 contains a kinase domain most closely related to the cyclin-dependent protein kinases which may activate cyclin-dependent kinase 2 and is involved in cell growth. CDK20 is a monomeric CAK that specifically phosphorylates CDK2 thr160 and functions as a CDK2-activating kinase. CDK20 is also a novel cyclin-dependent kinase-activating kinase in mammalian cells. CDK20 depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner.
• Form: 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~64 kDa
• Purity: >80%
• Applications: Western Blot
• Stability: 1 year at -70 centigrade from date of shipment
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 ug/uL

Gene Information

• Gene Name: CDK20 cyclin-dependent kinase 20 [ Homo sapiens ]
• Official Symbol: CDK20
• Synonyms: CDK20; cyclin-dependent kinase 20; CCRK, cell cycle related kinase; p42; CAK-kinase p42; CDK-activating kinase p42; cell cycle-related kinase; cell division protein kinase 20; cyclin-dependent protein kinase H; cyclin-kinase-activating kinase p42; P42; CCRK; CDCH; PNQALRE
• Gene ID: 23552
• mRNA Refseq: NM_001039803
• Protein Refseq: NP_001034892
• MIM: 610076
• UniProt ID: Q8IZL9
• Chromosome Location: 9q22.1
• Function: ATP binding; cyclin-dependent protein kinase activity; nucleotide binding