Recombinant Human CDH6 protein, His-tagged

• Cat.No.: CDH6-668H
• Product Overview: Recombinant Human CDH6 (Thr19-Ala615) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).

Specification

• Description: Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6/KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
• Source: HEK293
• Species: Human
• Tag: His
• Predicted N Terminal: Thr19
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 67.2 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Protein length: Thr19-Ala615
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >90% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: CDH6
• Official Symbol: CDH6
• Synonyms: CDH6; cadherin 6, type 2, K-cadherin (fetal kidney); cadherin-6; K Cadherin; CAD6; KCAD; FLJ14176; DKFZp564N1116
• Gene ID: 1004
• mRNA Refseq: NM_004932
• Protein Refseq: NP_004923
• MIM: 603007
• UniProt ID: P55285