Recombinant Human CDH18, GST-tagged

• Cat.No.: CDH18-11034H
• Product Overview: Recombinant Human CDH18 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 25-382a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CDH18 cadherin 18, type 2 [ Homo sapiens ]
• Official Symbol: CDH18
• Synonyms: CDH18; cadherin 18, type 2; cadherin-18; CDH14; EY CADHERIN; cadherin-14; ey-cadherin; cadherin-like 24; CDH24; CDH14L
• Gene ID: 1016
• mRNA Refseq: NM_001167667
• Protein Refseq: NP_001161139
• MIM: 603019
• UniProt ID: Q13634
• Chromosome Location: 5p14.3
• Pathway: Adherens junctions interactions, organism-specific biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-cell junction organization, organism-specific biosystem
• Function: calcium ion binding