Recombinant Human CDGSH Iron Sulfur Domain 1, His-tagged

• Cat.No.: CISD1-7153H
• Product Overview: Recombinant human CISD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 11.4 kDa.

Specification

• Description: CISD1 is a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT.
• Molecular Mass: 11.4 kDa (100aa) confirmed by MALDI-TOF
• Protein length: 32-108aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSKRFYVKD HRNKAMINLH IQKDNPKIVH AFDMEDLGDK AVYCRCWRSK KFPFCDGAHT KHNEETGDNV GPLIIKKKET
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CISD1 CDGSH iron sulfur domain 1 [ Homo sapiens ]
• Official Symbol: CISD1
• Synonyms: CISD1; CDGSH iron sulfur domain 1; C10orf70, chromosome 10 open reading frame 70 , ZCD1, zinc finger, CDGSH type domain 1; CDGSH iron-sulfur domain-containing protein 1; MDS029; mitoNEET; zinc finger CDGSH-type domain 1; zinc finger, CDGSH-type domain 1; CDGSH iron sulfur domain-containing protein 1; ZCD1; C10orf70; MGC14684
• Gene ID: 55847
• mRNA Refseq: NM_018464
• Protein Refseq: NP_060934
• MIM: 611932
• UniProt ID: Q9NZ45
• Chromosome Location: 10q21.3
• Pathway: Adipogenesis, organism-specific biosystem
• Function: 2 iron, 2 sulfur cluster binding; metal ion binding