Recombinant Human CDC73, His-tagged
Cat.No. : | CDC73-7927H |
Product Overview : | Recombinant Human Parafibromin is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2Glu260) of Human CDC73 fused with a 6His tag at the Nterminus. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | E.coli |
Tag : | His |
Description : | Parafibromin is expressed in the adrenal and parathyroid glands, kidney, and heart. As a tumor supressor, Parafibromin may be involved in transcriptional and posttranscriptional control pathways, also through the regulation of cyclin D1/PRAD1 expression, involved the cell cycle progression. Parafibromin is a component of the the PAF protein complex and interacts with a Set1like complex that has histone methyltransferase activity and methylates histone H3. Defects in Parafibromin can cause hyperparathyroidismjaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. |
Form : | Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.4 |
Purity : | Greater than 95% as determined by reducing SDS-PAGE. |
Notes : | For research use only. |
Storage : | Lyophilized protein should be stored at less than 20°C. though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C. for 2-7 days.Aliquots of reconstituted samples are stable at less than 20°C. for 3 months. |
Gene Name | CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) [ Homo sapiens ] |
Official Symbol | CDC73 |
Synonyms | CDC73; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); C1orf28, chromosome 1 open reading frame 28 , HRPT2, hyperparathyroidism 2 (with jaw tumor); parafibromin; hyperparathyroidism 2 protein; cell division cycle protein 73 homolog; HYX; HPTJT; HRPT2; C1orf28; FLJ23316; |
Gene ID | 79577 |
mRNA Refseq | NM_024529 |
Protein Refseq | NP_078805 |
MIM | 607393 |
UniProt ID | Q6P1J9 |
Chromosome Location | 1q25 |
Function | protein binding; |
◆ Recombinant Proteins | ||
CDC73-3153M | Recombinant Mouse CDC73 Protein | +Inquiry |
CDC73-597R | Recombinant Rhesus Macaque CDC73 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC73-7927H | Recombinant Human CDC73, His-tagged | +Inquiry |
CDC73-941R | Recombinant Rat CDC73 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC73-5180H | Recombinant Human CDC73 Protein (Met1-Glu260), N-His tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
CDC73-7645HCL | Recombinant Human CDC73 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All CDC73 Products
Required fields are marked with *
My Review for All CDC73 Products
Required fields are marked with *
0
Inquiry Basket