Recombinant Human CDC73, His-tagged

Cat.No. : CDC73-7927H
Product Overview : Recombinant Human Parafibromin is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2Glu260) of Human CDC73 fused with a 6His tag at the Nterminus.
  • Specification
  • Gene Information
  • Related Products
  • Download
Species : Human
Source : E.coli
Tag : His
Description : Parafibromin is expressed in the adrenal and parathyroid glands, kidney, and heart. As a tumor supressor, Parafibromin may be involved in transcriptional and posttranscriptional control pathways, also through the regulation of cyclin D1/PRAD1 expression, involved the cell cycle progression. Parafibromin is a component of the the PAF protein complex and interacts with a Set1like complex that has histone methyltransferase activity and methylates histone H3. Defects in Parafibromin can cause hyperparathyroidismjaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Form : Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.4
Purity : Greater than 95% as determined by reducing SDS-PAGE.
Notes : For research use only.
Storage : Lyophilized protein should be stored at less than 20°C. though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C. for 2-7 days.Aliquots of reconstituted samples are stable at less than 20°C. for 3 months.
Gene Name CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol CDC73
Synonyms CDC73; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); C1orf28, chromosome 1 open reading frame 28 , HRPT2, hyperparathyroidism 2 (with jaw tumor); parafibromin; hyperparathyroidism 2 protein; cell division cycle protein 73 homolog; HYX; HPTJT; HRPT2; C1orf28; FLJ23316;
Gene ID 79577
mRNA Refseq NM_024529
Protein Refseq NP_078805
MIM 607393
UniProt ID Q6P1J9
Chromosome Location 1q25
Function protein binding;

Not For Human Consumption!

Inquiry

  • Reviews
  • Q&As

Customer Reviews (0)

Write a review

Q&As (0)

Ask a question

Ask a Question for All CDC73 Products

Required fields are marked with *

My Review for All CDC73 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon